A novel ligand-independent peptide inhibitor of TREM-1 suppresses tumor growth in human lung cancer xenografts and prolongs survival of mice with lipopolysaccharide-induced septic shock

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A novel ligand-independent peptide inhibitor of TREM-1 suppresses tumor growth in human lung cancer xenografts and prolongs survival of mice with lipopolysaccharide-induced septic shock

Sigalov AB. Int Immunopharmacol. 2014

Diagnostic Magnetic Resonance Imaging of Atherosclerosis in Apolipoprotein E Knockout Mouse Model Using Macrophage-Targeted Gadolinium-Containing Synthetic Lipopeptide Nanoparticles

Shen ZT, Zheng S et al. PLoS One. 2015

Blockade of TREM-1 prevents vitreoretinal neovascularization in mice with oxygen-induced retinopathy

Rojas MA, Shen ZT et al. Biochim Biophys Acta Mol Basis Dis. 2018

Inhibition of TREM-2 markedly suppresses joint inflammation and damage in experimental arthritis

Sigalov AB. Int J Mol Sci. 2022

Rationally designed ligand-independent peptide inhibitors of TREM-1 ameliorate collagen-induced arthritis

Shen ZT and Sigalov AB. J Cell Mol Med. 2017

Nature-inspired nanoformulations for contrast-enhanced in vivo MR imaging of macrophages

Sigalov AB. Contrast Media Mol Imaging. 2014

SARS Coronavirus Fusion Peptide-Derived Sequence Suppresses Collagen-Induced Arthritis in DBA/1J Mice

Shen ZT and Sigalov AB. Sci Rep. 2016

The SCHOOL of nature: IV. Learning from viruses

Sigalov AB. Self Nonself. 2010

The SCHOOL of nature: III. From mechanistic understanding to novel therapies

Sigalov AB. Self Nonself. 2010

The SCHOOL of nature: II. Protein order, disorder and oligomericity in transmembrane signaling

Sigalov AB. Self Nonself. 2010